Protein Details: Aquaporin AQPcic

Protein ID

ICDB_Pro_0869

Protein Name

Aquaporin AQPcic

Gene Name

AQP; CIC

Organism

Cicadella viridis (Green leafhopper)

Length

255 amino acids

AlphaFoldDB

AF-Q23808-F1-model_v4.pdb

Function

Forms a water-specific channel. May be involved in the transfer of excess sap dietary water from the initial midgut to the terminal midgut and the proximal part of the malpighian tubules.

Sequence

MAADKSVDNTKKIIGIDDITDTKTIWRCLAAELIGTLLLVLIGTGSCTGVQISEGDVVVRIALTFGFIIATMVQCIGHVSGCHINPAVTCGLLVTGHISILKAIFYIIVQCVGAIAGSAILKVITPAEFRGTLCMTSLAPGVTPPMGFLVEACITFVLILLVQSVCDDRRKNLGNAAPVAVGLAITCCHLAAIKYTGSSMNPARSFGPAVNGDDNWANHWVYWAGPIVGGVVAGITYRALFRARKPEEEASSYDF

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Filter chamber epithelium in the digestive tract. Absent from midgut.

DOI ID

10.1111/j.1432-1033.1996.00707.x; 10.1074/jbc.270.29.17414